When the national anthem was played before the start of the game, some 49ers knelt while some Colts, their arms locked, wore black T-shirts with the words "We Will" on the front and "Stand for equality, justice, unity, respect, dialogue, opportunity" on the back.
Woods and Mickelson previously played a pay-per-view exhibition in November 2018 that was beset with technical difficulties and ultimately streamed for free.
Tiger Woods and Peyton Manning held off a late challenge to beat Phil Mickelson and Tom Brady 1Up in a charity golf match in Florida on Sunday that raised $20 million for COVID-19 relief efforts.